ESAC Inc.

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June 2, 2014 Issue

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Biomedical Data Services for Academic, Commercial and Government Clients

About ESAC Inc.
www.esacinc.com

ESAC, Inc. provides research data management, bioinformatics, and healthcare information technology solutions for government, commercial and academic clients. Headquartered in Rockville, MD, our mission is to play a vital role in helping clinicians, scientists and researchers across the globe improve all aspects of human health. ESAC currently employs more than 35 scientific and technical personnel. Most of our staff holds advanced degrees providing subject matter expertise and support to critical government programs such National Cancer Institute/NIH initiatives involving large-scale data management and visualization; and the Office of the National Coordinator on Health IT, where ESAC is developing and implementing the standards and interoperability framework for electronic health records.

Shine Jacob

President

Shine Jacob is the founder and President of Enterprise Science and Computing (ESAC), Inc. a fast growing small business focused in healthcare IT, research data management, and biomedical technology solutions. Mr. Jacob is an innovative technology leader with expertise in life sciences project and program management. He is currently leading initiatives on the forefront of big data wrangling in the biomedical sciences through management and analysis of research data in support of various Federal government programs. Since founding ESAC in 2006, Mr. Jacob has driven the company’s revenue growth by over 130%, landing ESAC on both the INC-500 for the past two years, and Washington Technology’s list of 50 fastest growing small-businesses in the government technology market for both 2012 and 2013. Mr. Jacob and his firm oversee and lead the design, development, and deployment of several bioinformatics solutions, and scientific databases in support of agencies within the Department of Health and Human Services, as well as private sector clients. Prior to founding ESAC, Mr. Jacob held key positions at Celera Genomics driving leading-edge initiatives related to knowledge management, proteomics, scientific data warehousing, and small molecule drug development programs. Mr. Jacob holds an M.S. in Information Technology from John Hopkins University, and is a certified Scrum Master and a certified Project Management Professional (PMP). He resides in North Potomac, Maryland with his wife and 5 children.

“We believe the government turns to ESAC because we are a small business that can rapidly adapt to the ever changing requirements in healthcare IT. We also have a workforce that includes both talented software engineers and doctoral level biomedical scientists who know the data well and speak the language of the HHS agencies and other healthcare stakeholders.” - Shine Jacob


ESAC Inc.
155 Gibbs St, Suite 420
Rockville, MD 20850-0389

855-372-2462

www.esacinc.com


 

 

 

Interview conducted by: Lynn Fosse, Senior Editor, CEOCFO Magazine, Published – June 2, 2014
 

CEOCFO: Mr. Jacob, what is the concept for ESAC?
Mr. Jacob:
ESAC stands for Enterprise, Science and Computing. We provide services in the very niche area of healthcare IT, Bioinformatics, and Research Data Management. The concept for ESAC stemmed from my work at Celera during the early part of the millennium when the genomics revolution was beginning. There was (and still is) a huge demand for visualizing, managing, integrating, and making sense of the enormous troves of growing biomedical data. I knew my colleagues and I could contribute to that niche since we were there from the beginning. Our focus is to help improve global health by enabling technology to convert biomedical data to knowledge.

 

CEOCFO: Would you tell us about the elements in your technology that will lead to better healthcare? What is the process?
Mr. Jacob:
Our mission is service oriented rather than selling IT projects to the healthcare market. We primarily use existing technology tools to build software and database solutions specific to our clients’ needs. We do not have our own products yet, but that could be a future direction. What we have is a group of subject matter experts and technologists, with educational and professional experience in dealing with biomedical and healthcare related concepts and frameworks. That is where we make the difference. We specialize in project management and software development specific to the life sciences and healthcare.

 

CEOCFO: What are some of the challenges in taking life science data and putting it into a usable format?
Mr. Jacob:
Life science data are changing daily. And the data are growing, so there is a large amount of information to deal with. There are three primary challenges for taming and filtering this data into a useable format: 1. Data storage, 2. harmonization, and 3. visualization within different contexts. Data standards are not there for many data types. Data must be harmonized within a community or a set of users otherwise large-scale data integration from multiple sources is impossible. Working with research consortiums and subject matter experts to standardize data for harmonization is critical. Cloud computing is tackling the problem of data storage, however, there are significant costs associated with this storage, so people need to be more vigilant about deleting raw data that has been analyzed. People worry about losing their raw data if needed down the road, but data generation is actually less costly than storage. Finally, user-friendly data visualization and the ability to query the data is critical. Biomedical researchers will have different visualization needs than clinicians, who need quick summary reports. At ESAC we do significant background and prep work prior to initiating new projects so that we understand the challenges, variables, and what the outcome should be to best position ourselves for success.

 

CEOCFO: How do you keep up with all of the changes in not only healthcare, but also technology?
Mr. Jacob:
We spend a significant amount of time staying on top of the latest research and methods published in the literature and through networking at conferences. We strive to determine the gaps in healthcare technology needs and often develop our own solutions in close consultation with our clients. Many on our staff have doctoral degrees and work closely with the leading subject matter experts who are working on the front line of healthcare issues and emerging technologies and innovations. Ongoing training and professional development is key to keeping our staff current on the ever changing landscape in healthcare related technologies.

 

CEOCFO: What types of companies or government agencies are you working with?
Mr. Jacob:
Most of our work is within Health and Human Services, which includes NIH, the National Cancer Institute, the Office of National Coordinator, and Centers for Medicare and Medicaid Services. We are currently pursuing opportunities with the Centers for Disease Control, and the Agency for Healthcare Research and Quality. In addition, ESAC also works with the private sector and academic institutions that are working with large healthcare datasets.

 

CEOCFO: What types of projects would the government look to outsource and why would they come to you?
Mr. Jacob:
We believe the government will continue to look to the contractor community to meet its needs in data management and information systems in the healthcare domain. The challenge is not only managing extremely large data sets, but also performing the science and analyses to optimize the knowledge that comes from mining the data. We believe the government turns to ESAC because we are a small business that can rapidly adapt to the ever changing requirements in healthcare IT. We also have a workforce that includes both talented software engineers and doctoral level biomedical scientists who know the data well and speak the language of the NIH and other healthcare stakeholders. We believe the government will continue to turn to ESAC to continue the monumental task of developing the standards for a Health Information Exchange and how various disparate systems will exchange and share information. This type of work requires very specific subject matter expertise not only in Healthcare IT, but also in the biomedical domain.

 

CEOCFO: Do agencies come to you? Is there a bidding process? Do you look at projects to bid on? How does it work?
Mr. Jacob:
We have developed a reputation for providing exceptional performance and delivering on our existing contracts, which often results in agencies contacting us for support. As a certified 8(a) small business, ESAC has been fortunate to be awarded a number of contracts on a sole source or restricted competitive basis. More recently, we have actively pursued solicitations that call for our science and healthcare IT expertise. In addition, we often partner with research institutions and large businesses in pursuit of these opportunities, as building strong partnerships are key to sustained business growth. In all cases, we go through a rigorous bidding and negotiation process.

 

CEOCFO: What have you learned either from previous experiences or at ESAC about how to tell when a project is really worthwhile?
Mr. Jacob:
We have learned that often our understanding of the scope work is different when you are bidding on a project then when you are executing the project. Some projects are short term while other span over multiple years. Requirements get refined during the performance; so managing change and controlling cost is critical to delivering the project on time and within budget. We have also learned that if a contract is issued on a fixed price basis, there is less flexibility to accommodate changes and it is important to proactively communicate and manage the expectations of the client. We do our best to understand the requirements in detail when deciding to bid on a project so we can develop a realistic estimate to perform the work. We find ourselves pursing work that is exciting and challenging and in areas where our staff are passionate.

 

CEOCFO: Your website has the words, “innovation and innovate”, in several places. Would you give us an example of something that you have developed that would fall into that innovative category?
Mr. Jacob:
An example that comes to mind is where we have developed a database that integrates patient clinical data (age, lifestyle habits etc.) with a variety of biomedical research data types in a unified database environment. While a number of rich data repositories for high throughput research data exist in the public domain, many tend to focus on a single data type and do not support the integration across multiple technologies. By integrating clinical data with high throughput gene-based molecular data, researchers will be able to determine which treatment works best for a patient based on their genome. By tracking and integrating thousands of patient data points, researchers can analyze this data to provide clinicians with personalized information for their patients so they can modify treatment methods to achieve improved health outcomes. Another example of innovation is where we have used emerging technologies to facilitate the sharing of enormous datasets among stakeholders. Until recently, these large datasets could not be shared via the Internet. We have partnered with Aspera, which has enabled downloading of tremendous amounts of data in a secure and fast manner.

 

CEOCFO: What is ahead for the company?
Mr. Jacob:
We will continue to focus on what we do well in an effort to grow our client base. For now, we believe staying focused in our sweet spot provides an advantage over larger competitors with a broader portfolio. Our emphasis is in very specific areas supporting the mission of our customers –applying our expertise in healthcare, biomedical and technology, to improve all aspects of human health.

 

CEOCFO: Why pay attention to ESAC today? Why does the company stand out?
Mr. Jacob:
We are a services company that is working closely with the government and other organizations to establish the standards for information sharing of healthcare data. Our staff is made up of subject matter experts and leaders in a rapidly changing and challenging space. Unlike most IT companies, we sit at the cross section of science and technology, allowing us to develop innovative solutions to challenging problems. We are small and agile, and meeting the customer’s needs is of paramount importance to everything we do. These are our unique differentiators. .

 

CEOCFO: What is your day-to-day focus as CEO?
Mr. Jacob:
Although one of my critical roles is to identify new opportunities to continue the company’s growth and offer our staff increased challenges, I am still actively involved in the day-to-day operations of the company. My technical training allows me to keep my hands in the management and technical aspects of the project, but I am also spending time wearing the hats of the CEO/COO/CFO and focusing more time on driving the strategic direction of the company. I am fortunate to have ESAC’s Vice President, Mike Flanigan, as my partner in helping for most of the day-to-day operations as well as strategic matters.

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